| Meade Instruments | Irvine | 1972 |
| MedImmune | Gaithersburg | 1988 |
| Memorex | Cerritos | 1961 |
| Mercer Motors Corporation | New Britain | 1909 |
| Merck & Co. | Rahway | 1891 |
| Metropolitan Life Insurance Company | Nueva York | 24 de marzo de 1868 |
| MGA Entertainment | Los Ángeles | 1979 |
| Micro Instrumentation and Telemetry Systems | Albuquerque | 1970 |
| Microchip Technology Inc. | Chandler | 1989 |
| Milwaukee Electric Tool Corporation | Brookfield | 1924 |
| Missouri Pacific Railroad | San Luis | 1917 |
| MITRE Corporation | Bedford | 1958 |
| Modulus Graphite | Richmond | 1978 |
| Mondelēz International | Chicago | 2012 |
| MoneyGram | Dallas | 1940 |
| Monster Inc. | Brisbane | 1978 |
| Monster.com | Guaynabo | 1999 |
| Moog Music | Asheville | 1953 |
| MoPar | Chrysler Auburn Hills | 1933 |
| MOS Technology | Norristown | 1969 |
| Motorola Inc. | Schaumburg | 25 de septiembre de 1928 |
| National Association of Underwater Instructors | Florida | 1959 |
| National Oilwell Varco | Houston | 1862 |
| National Semiconductor | Santa Clara | 1959 |
| National Wrestling Alliance | Houston | 1948 |
| Nautica | Nueva York | 1983 |
| Navteq | Chicago | 1985 |
| NCR | Atlanta, Augsburgo | 1884 |
| Neon | Nueva York | 2017 |
| NetJets | Columbus | 1964 |
| NetSuite | Austin | 1998 |
| Neuberger Berman | Nueva York | 1939 |
| New York Mercantile Exchange | Nueva York | 1872 |
| Newegg | Industry | 2001 |
| Noble Energy | Houston | 1932 |
| Nomura Securities | Nihonbashi, Tokio | 7 de mayo de 2001 |
| Nordstrom | Seattle | 1901 |
| North American Arms | Provo | 1972 |
| Northern Trust | Illinois, Chicago | 1889 |
| Northwestern Mutual | Milwaukee | 1857 |
| NRG Energy | Princeton, Houston | 1905 |
| Nullsoft | Phoenix | 1997 |
| Nutanix | San José | 2009 |
| NZXT | Los Ángeles | 2004 |
| O'Reilly Auto Parts | Springfield | 1957 |
| Oakley, Inc. | Foothill Ranch | 1975 |
| Oberheim | Oakland | 1969 |
| Obsidian Entertainment | Irvine | 12 de junio de 2003 |