| Abbott-Detroit | Detroit | 1909 |
| AM General | South Bend | 1971 |
| American Austin Car Company | Butler, Delaware | 1929 |
| American Motors Corporation | Kenosha | 1954 |
| Buick | Detroit | diciembre 1899 |
| Cadillac | Detroit | 1902 |
| Camionetas Ram | Auburn Hills | 2010 |
| Canoo | Torrance | 2017 |
| Carroll Shelby International | Enterprise | 17 de agosto de 1962 |
| Cartercar | Pontiac | 1905 |
| Chalmers Automobile | Detroit | 1908 |
| Checker Motors Corporation | Kalamazoo | 1922 |
| Detroit Diesel | Detroit | 1938 |
| Detroit Electric Car Company | Detroit | 1907 |
| Diamond-Star Motors | — | octubre 1985 |
| Dodge | Dodge Building | 14 de diciembre de 1900 |
| Duesenberg | Indianápolis | 1913 |
| Faraday Future | Gardena | 2014 |
| General Motors | Detroit | 16 de septiembre de 1908 |
| Global Electric Motorcars | Fargo | 1992 |
| Jeep | Toledo | 1941 |
| Kaiser Jeep | Toledo | 1953 |
| Lincoln Motor Company | Dearborn | 1917 |
| Local Motors | Phoenix | 2007 |
| Oldsmobile | Lansing | 1897 |
| Overland Automobile Company | Indianápolis | 1903 |
| Peerless | Cleveland | 1900 |
| PhoenixEV | Ontario | 2002 |
| Rickenbacker | Detroit | 1921 |
| Saleen | Corona | 1983 |
| Saturn Corporation | Spring Hill | 1985 |
| Scripps-Booth | Detroit | 1913 |
| Shelby SuperCars | West Richland | 1999 |
| Stanley | Newton | 1902 |
| Stellantis North America | Chrysler Auburn Hills | 28 de abril de 2009 |
| Studebaker-Packard Corporation | Detroit | 1954 |
| Thomas Built Buses | High Point | 1972 |
| VLF Automotive | Rochester | 2015 |
| Waymo | Mountain View | 13 de diciembre de 2016 |
| Zimmer | Siracusa | 1978 |